Rob Dowdeswell

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OBJECTIVE To describe the association between isoniazid preventive therapy (IPT) and mortality among individuals starting antiretroviral therapy (ART) in a workplace programme in South Africa where tuberculosis (TB) incidence is very high. METHODS ART-naive individuals starting ART from January 2004 to December 2007 were followed for up to 12 months.(More)
BACKGROUND Traditional tuberculosis (TB) treatment outcome measures, such as cure rate, do not provide insight into the underlying reasons for missing clinical targets. We evaluated a TB Process-Based Performance Review (TB-PBPR) tool, developed to identify "missed opportunities" for timely and accurate diagnosis of TB. The tool enables performance(More)
The aim was to determine reliability of lung function measurements performed according to recommendations of the American Thoracic Society (ATS) at a screening program in a large South African gold mine and to determine the usefulness of the reliability coefficient G for monitoring the reliability of lung function measurements in a mass screening program.(More)
Electrical impedance spectroscopy was used to monitor the development of a maturing differentiated state of mono-layers of cells during culture. The cells utilised in this study were the endotheliallike cell line ECV304 and the epithelial colonic cell line Caco2. The cells were grown on a permeable support membrane in mono-culture and following co-culture(More)
Carbuterol tablets (2,0 mg) were compared with the tablets of fenoterol (2,5 mg) and hexoprenaline (1 mg). The three drugs were shown to be equally effective for a period of 4 hours, but carbuterol and fenoterol exerted a statistically significant bronchodilating action for 7 and 8 hours respectively, while the action of hexoprenaline lasted for 4 hours in(More)
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