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PURPOSE Tuberous sclerosis complex (OMIM 191100) is a multiorgan disease commonly associated with epilepsy refractory to anticonvulsants. Individual reports indicate that seizures in children with tuberous sclerosis might benefit from a ketogenic diet. We studied the effects of the diet introduced at 3.5 years of age in three boys with tuberous sclerosis(More)
OBJECTIVE The aim of this study was to assess how the ketogenic diet influences the blood levels of antiepileptic drugs in the first month of treatment in a pediatric population with drug-resistant epilepsy. METHODS The plasma concentrations of antiepileptic drugs were investigated in an open study on 36 consecutive children and adolescents (20 males),(More)
The authors describe a case of a female obese patient with cushingoid habitus who was not suffering from Cushing's syndrome or disease but from empty sella syndrome. The authors emphasize the importance of a systematic search for possible causes of obesity, especially if it joins with a particular habitus.
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