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  • Penny Bryant, Martin Pabst, +23 authors Antony Godwin
  • Chemistry, Medicine
  • Molecular pharmaceutics
  • 2015 (First Publication: 5 May 2015)
  • The conjugation of monomethyl auristatin E (MMAE) to trastuzumab using a reduction bis-alkylation approach that is capable of rebridging reduced (native) antibody interchain disulfide bonds has beenContinue Reading
  • Karolina Peciak, Emmanuelle Laurine, Rita Tommasi, Ji-Won Choi, Steve Brocchini
  • Chemistry, Medicine
  • Chemical science
  • 2019 (First Publication: 9 October 2018)
  • Site-selective conjugation generally requires both (i) molecular engineering of the protein of interest to introduce a conjugation site at a defined location and (ii) a site-specific conjugationContinue Reading
  • Francesco Iacuzzo, Stefano Gottardi, +7 authors Stefano Cesco
  • Medicine, Chemistry
  • Journal of the science of food and agriculture
  • 2011 (First Publication: 30 January 2011)
  • BACKGROUND Unbalanced nutrient availability causes disequilibrated plant growth, which can result in a worsening of harvested product quality, such as high nitrate content in edible tissues. To copeContinue Reading