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In order to develop a simple, efficient system for the high-level expression of human insulin receptors in eukaryotic cells, a full-length human kidney insulin receptor cDNA was inserted into a bovine papilloma virus vector under the control of the mouse metallothionein promoter. After transfection of mouse NIH 3T3 cells with this construct, seven cell(More)
Influenza is a common viral infection, which presents as a mild illness in most healthy adults but is responsible for significant morbidity among vulnerable groups such as the elderly, patients with underlying conditions and children. Vaccination against influenza is one of the most effective tools to protect against the disease and its complications.(More)
The purpose of this study is to determine the place of trapeziectomy among the various surgical treatments of osteoarthritis of the trapezio-metacarpal joint. We have had 25 cases with seemingly satisfactory results. Loss of strength, which is given as a frequent objection to this method, has not generally been found in our series. Careful repair of the(More)