Author pages are created from data sourced from our academic publisher partnerships and public sources.
Restoration of the transcription activation function to mutant p53 in human cancer cells.
The p53 tumor suppressor gene product is a sequence-specific transcription activator frequently mutated in a variety of human malignancies. Typically, tumor-derived p53 missense mutants are defective… Expand
The Analysis of H-2 Mutants: Molecular Genetics and Structure/Function Relationships
The class I genes of the murine major histocompatibility complex are located in four regions (K, D, Qa, Tla) along chromosome 17. The K and D regions contain the genes encoding the classical H-2… Expand