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Eye drops are widely accepted as formulations for targeting the anterior segment notwithstanding their limitations in terms of bioavailability. The unique structure of the eye requires… (More)
Thermoreversible gels formed in situ by oil-in-water microemulsion were evaluated to improve topical delivery of griseofulvin (GF), a fungi-static antibiotic chosen as a sparingly soluble model drug.… (More)
Vancomycin (Vm) currently represents the gold standard against methicillin-resistant Staphylococcus aureus (MRSA) infections. However, it is associated with low oral bioavailability, formulation… (More)
Microemulsions prepared using 1-decanol, oleic acid or oleyl alcohol as oils, Transcutol and 1, 2- hexanediol as surfactant mixture and phosphate buffer pH 6.0 as aqueous phase were studied to verify… (More)
Acyclovir is not a good candidate for passive permeation since its polarity and solubility limit is partitioning into the stratum corneum. This work aims to develop a new topical formulation for the… (More)
Background: Peritoneal carcinomatosis is a common metastatic pattern in ovarian, gastric, colorectal, and appendiceal cancer; systemic chemotherapy is the current standard of care for peritoneal… (More)