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Multidrug- (MDR) and extensively drug resistant (XDR) tuberculosis (TB) presents a challenge to disease control and elimination goals. In Lisbon, Portugal, specific and successful XDR-TB strains have been found in circulation for almost two decades. In the present study we have genotyped and sequenced the genomes of 56 Mycobacterium tuberculosis isolates(More)
Description: This book describes the potentialities of metaheuristics for solving production scheduling problems and the relationship between these two fields. For the past several years, there has been an increasing interest in using metaheuristic methods to solve scheduling problems. The main reasons for this are that such problems are generally hard to(More)
This work presents a tool to support authentication studies of paintings attributed to the modernist Portuguese artist Amadeo de Souza-Cardoso (1887-1918). The strategy adopted was to quantify and combine the information extracted from the analysis of the brushstroke with information on the pigments present in the paintings. The brushstroke analysis was(More)