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  • John F. Cryan, Rita J Valentino, Irwin Lucki
  • Psychology, Medicine
  • Neuroscience & Biobehavioral Reviews
  • 2005 (First Publication: 31 December 2005)
  • Selective serotonin reuptake inhibitors (SSRIs) are the most widely prescribed antidepressant class today and exert their antidepressant-like effects by increasing synaptic concentrations ofContinue Reading
  • Elisabeth J. Van Bockstaele, Eric E. O. Colago, Rita J Valentino
  • Biology, Medicine
  • Journal of neuroendocrinology
  • 1998 (First Publication: 21 August 2006)
  • Corticotropin-releasing factor (CRF), the neurohormone that initiates the endocrine limb of the stress response via its actions on the anterior pituitary, also acts as a neurotransmitter in theContinue Reading
  • Jenna C. Carroll, Michiyo Iba, +5 authors John Q. Trojanowski
  • Biology, Medicine
  • The Journal of Neuroscience
  • 2011 (First Publication: 5 October 2011)
  • Because overactivation of the hypothalamic–pituitary–adrenal (HPA) axis occurs in Alzheimer's disease (AD), dysregulation of stress neuromediators may play a mechanistic role in the pathophysiologyContinue Reading
  • Susan K. Wood, Hayley E. Walker, Rita J Valentino, Seema Bhatnagar
  • Biology, Medicine
  • Endocrinology
  • 2010 (First Publication: 1 April 2010)
  • Previous social stress exposure is a common risk factor for affective disorders. However, factors that determine vulnerability or resiliency to social stress-induced psychopathologies remain unclear.Continue Reading
  • Debra A. Bangasser, Andre L. Curtis, +5 authors Rita J Valentino
  • Psychology, Medicine
  • Molecular Psychiatry
  • 2010 (First Publication: 17 May 2010)
  • Although the higher incidence of stress-related psychiatric disorders in females is well documented, its basis is unknown. Here, we show that the receptor for corticotropin-releasing factor (CRF),Continue Reading
  • Andre L. Curtis, Sandra M. Lechner, Luis A. Pavcovich, Rita J Valentino
  • Chemistry, Medicine
  • The Journal of pharmacology and experimental…
  • 1997 (First Publication: 1 April 1997)
  • Corticotropin-releasing factor (CRF) administered intracerebroventricularly (i.c.v.) activates noradrenergic locus coeruleus (LC) neurons of halothane-anesthetized and unanesthetized rats. This studyContinue Reading
  • Lynn G. Kirby, Luise I. M. Pernar, Rita J Valentino, Sheryl G. Beck
  • Biology, Medicine
  • Neuroscience
  • 2003 (First Publication: 1 February 2003)
  • The membrane properties and receptor-mediated responses of rat dorsal raphe nucleus neurons were measured using intracellular recording techniques in a slice preparation. After each experiment, theContinue Reading