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OBJECTIVE We hypothesized that a subgroup of patients with frank stroke due to sudden occlusion of the internal carotid artery could safely undergo surgery to restore carotid patency and to rescue brain tissue not yet irreversibly damaged if current stroke diagnostic methods were applied. METHODS From November 1997 to March 2007, 1810 patients underwent(More)
We compared gene expression profiles in acutely dissected aorta with those in normal control aorta. Ascending aorta specimen from patients with an acute Stanford A-dissection were taken during surgery and compared with those from normal ascending aorta from multiorgan donors using the BD Atlas™ Human1.2 Array I, BD Atlas™ Human Cardiovascular Array and the(More)
Peripheral arterial disease (PAD) is not an uncommon but a commonly neglected condition by many medical practitioners. Its prevalence steadily increases with age. In Germany almost one fifth of the patients aged > 65 years suffer from it. With increasing life expectancy the prevalence of PAD seems to be on the increase. PAD is a manifestation of diffuse and(More)
In 124 selected autopsy cases we found 27 cases with so-called hypoplastic zones in scrotal and otherwise normal testes. In seven cases both sides were affected. The frequency of hypoplastic zones diminishes with increasing age. The significance of this fact is discussed. We conclude that hypoplastic zones should not be considered as a sign of major(More)
Arterial hypertension is most often the first symptom of renal artery stenosis (RAS). Appropriate screening methods for the diagnostic workup of hypertension are colour-coded duplex ultrasound and captopril scintigraphy. Angiography (intraarterial digital subtraction angiography) represents the diagnostic "gold standard", which is the prerequisite for the(More)
Untersucht wurde der gegenwärtige Stellenwert der Revaskularisation eines akuten Karotisverschluss im akuten Insult. Von 1997–2006 wurden innerhalb einer kontinuierlichen Serie 34 Patienten mit einem akuten Karotisverschluss prospektiv erfasst, die wir innerhalb von 72 h (Durchschnitt 25 h) nach Symptombeginn und innerhalb von 36 h (Durchschnitt 16 h) nach(More)
17 lokale Muskelplastiken wurden zur Weichteildeckung bei 13 offenen Unterschenkelfrakturen (1° bis 4°) und vier chronischen Ostitiden mit instabilen Narben durchgeführt. Hierbei waren der Musculus soleus 16mal ausschließlich oder in Kombination mit dem Musculus gastrocnemius (dreimal), Musculus hallucis longus (einmal) oder Musculus tibialis anterior(More)
BACKGROUND Cerebral microembolic signals (MES) after carotid endarterectomy (CEA) are associated with an increased risk of postoperative stroke. We investigated the relationship of an intraoperatively recorded ultrasound turbulence index (TI) during CEA and the occurrence of MES. METHODS Short-time MES detection was performed on 164 patients (mean age 64(More)