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Ninety-five patients with bipolar manicdepressive disorders were followed from 1959 to 1975, and their first-degree relatives (N=617) were studied. In the search for heterogeneity of bipolar illness the patients were subclassified according to various criteria: sex, age at onset, number of episodes, and longitudinal syndrome subtypes (Dm, MD, Md), and the(More)
Severely alcohol intoxicated patients pass through all stages of anesthesia according to the Guedel classification. Additional illnesses or injuries might be present, however. These require careful investigation. Blood alcohol levels are no criterion for the degree of intoxication. The treatment varies and is based on clinical symptoms. In our series of(More)
The lower oesophageal sphincter plays an important role as a gastro-oesophageal blocker. Its proper function as a reflux barrier for the prevention of regurgitation and aspiration during anesthesia is very important. Therefore the effect of inhalation anesthetics upon the lower oesophageal sphincter is of great interest. In 10 healthy volunteers we studied(More)