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1. The transient current required to impose a step charge of potential has a complex time course especially in the region of internal potential between -50 and -40 mV. 2. Examination of non-linear transient current in this voltage range suggests two components of charge movement: (a) an initial more-or-less exponential movement, and (b) a slower component(More)
1. Membrane capacity of sartorius muscle fibres has been measured at membrane potentials between -200 and +50 mV. Within this potential range the capacity is not independent of potential. Dielectric saturation is present at large negative and at positive internal potentials, indicating the presence in the membrane of permanent dipoles or movable charges. 2.(More)
1. Muscle fibres from goats with myotonia congenita show characteristic responses to stimulation with intracellular currents (Adrian & Bryant, 1974). To test whether the reduced surface chloride conductance can account for these myotonic discharges, we have calculated responses of a model 'muscle fibre' to intracellular current of long duration (greater(More)
We assembled data from a global network of automated lake observatories to test hypotheses regarding the drivers of ecosystem metabolism. We estimated daily rates of respiration and gross primary production (GPP) for up to a full year in each lake, via maximum likelihood fits of a free-water metabolism model to continuous high-frequency measurements of(More)
Key Points: • Lake surface waters are warming rapidly but are spatially heterogeneous • Ice-covered lakes are typically warming at rates greater than air temperatures • Both geomorphic and climate factors influence lake warming rates Supporting Information: • Figures S1–S4 and Tables S1–S4 Citation: O'Reilly, C. M., et al. (2015), Rapid and highly variable(More)
In Europe, the effects of global warming are expected to be particularly acute in areas exposed to a more extreme continental climate. The climate change scenarios summarized in Chapter 2, this volume, suggest that the average summer temperatures in some areas of Central Europe could increase by as much as 6 • C by 2071–2100. The associated projections for(More)
1. Intramembrane charge movement has been measured in striated muscle subjected to prolonged depolarization but repolarized to -100 mV for up to 100 sec. The method of measurement allows identification of charge or charges which are 'reprimed' by repolarization. 2. Charge 'reprimed' by repolarization appears to differ in its voltage distribution from charge(More)
Limnologists and water resources managers have traditionally perceived lakes as discrete geographical entities. This has resulted in a tendency for scientific lake studies to concentrate on lakes as individuals, with little connection either to each other or to large-scale driving forces. Since the 1990s, however, a shift in the prevailing paradigm has(More)