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The potential role of neuroinflammation and transcription factors in Parkinson disease
TLDR
An increased level of inducible nitric oxide synthase observed in the substantia nigra and striatum of PD patients suggests that both cytokine—and chemokine-induced toxicity and inflammation lead to oxidative stress that contributes to degeneration of dopaminergic neurons and to disease progression.
Role of neuroinflammation and latent transcription factors in pathogenesis of Parkinson’s disease
TLDR
It is said that transcription factors promoting inflammation such as NF-κB, STAT 3, AP 1, and Toll-like receptors are constitutively upregulated in PD, while neuroprotective pathways such as mTOR, TGF-β, and YY1 are substantially downregulated in microglia of PD patients.
Antihyperglycemic and antihyperlipidemic effects of Salvadora persica in streptozotocin-induced diabetic rats
TLDR
The research suggests that the S. persica root extract was significantly effective when compared with control and standard in the treatment of hyperlipidemia and hyperglycemia in diabetic rats, and may be beneficial to diabetic patients.
Protective effects of different antioxidants against endosulfan-induced oxidative stress and immunotoxicity in albino rats.
TLDR
A significant attenuation of the oxidative stress markers and immunotoxicity with a combined therapy of L-ascorbic acid plus alpha-tocopherol and with N-acetylcysteine was clearly demonstrated by the present results.
Pharmacological and biochemical studies on the protective effects of melatonin during stress-induced behavioral and immunological changes in relation to oxidative stress in rats.
TLDR
It is concluded that melatonin may have a protective role during stress-induced neurobehavioral and immunological changes in rats, and the involvement of free radicals during stressed periods is strongly suggestive of the role of oxidative stress markers.
Effect of Boswellia Serrata Extract on Acute Inflammatory Parameters and Tumor Necrosis Factor-α in Complete Freund's Adjuvant-Induced Animal Model of Rheumatoid Arthritis
TLDR
BSE at dose 180 mg/kg showed statistically significant improvement in body weight and decrease in ankle diameter and arthritic index and might have usefulness as an adjunct to conventional therapy of RA.
ANTIOXIDANT POTENTIAL AND FREE RADICALS SCAVENGING ACTIVITY BY POD EXTRACTS OF ACACIA SENEGAL WILLD
Acacia Senegal Willd (Leguminosae), known as Arabic gum tree. Its mature pods with seeds were extracted using solvents of different polarities and explored for in-vitro free radical scavenging
Studies on character interrelationship in clonal generation of sugarcane (Saccharum complex Hybrids)
TLDR
Correlations and path co-efficient were studied in Saccharum complex hybrids clones and revealed that stalk height itself was not an important trait for direct selection for higher cane and sugar yield.
Genetic variability, heritability and genetic advance in bread wheat (Triticum aestivum L.).
Thirty genotypes of bread wheat were evaluated in randomized block design (RBD) with three replications for yield and yield contributing traits during rabi 2007-2008, find out genetic variability,
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