Learn More
Tumor associated antigens from pooled allogeneic membrane proteins were isolated, partially purified and tested as a possible vaccine in patients with stage II and III colon cancer. The vaccine, when given in combination with an adjuvant following surgical resection, resulted in marked improvement in survival compared to control patients having only(More)
Monoclonal antibodies developed against immunogenic proteins (Tumor Specific Antigens/TSA's) that are expressed in human cancers, display a unique behavioral pattern. They appear to serve in a dual role. This includes the early recognition of these immunogenic membrane proteins that can serve as diagnostic markers, and the targeting of such markers for the(More)
Central pontine myelinolysis is a demyelinating condition affecting the pons characterized by an acute progressive quadriplegia, dysarthria, dysphagia, and alterations of consciousness. Pathologic features include prominent demyelination in the central pons with sparing of axons and neurons. This condition is usually associated with systemic disorders such(More)
CONTEXT Retention in treatment can improve the outcomes of patients with substance use disorders. AIMS This study aimed to assess the predictors of treatment retention in a set of patients admitted with substance use disorders. SETTING AND DESIGN This record-based study was conducted among consecutive patients discharged from the inpatient unit of a(More)
BACKGROUND No study from India has examined pathways to care in alcohol using population systematically. OBJECTIVES The present study aimed to understand the pathways to care among alcohol-dependent individuals seeking help at a tertiary care center. PATIENTS AND METHODS It was a cross-sectional, observational study. A total of 58 subjects diagnosed(More)
BACKGROUND AND AIMS Patients with diabetes mellitus frequently experience erectile dysfunction. This systematic review and meta-analysis were conducted to find efficacy and tolerability of phosphodiesterase 5 (PDE5) inhibitors in patients with diabetes mellitus experiencing erectile dysfunction. METHODOLOGY Electronic searches were carried out to identify(More)
BACKGROUND Virchow Robin spaces (VRSs) are perivascular spaces that act as drainage pathways for interstitial fluid. Dilatation of VRSs is visible on magnetic resonance images in asymptomatic individuals. However, giant dilatation of VRSs (dVRSs) is very rare. Such giant dVRSs may produce a pressure effect on surrounding structures and can be confused with(More)