Risa J Lin

Learn More
The Real-time Experiment Interface (RTXI) is a fast and versatile real-time biological experimentation system based on Real-Time Linux. RTXI is open source and free, can be used with an extensive range of experimentation hardware, and can be run on Linux or Windows computers (when using the Live CD). RTXI is currently used extensively for two experiment(More)
In previous studies we used the technique of dynamic clamp to study how temporal modulation of inhibitory and excitatory inputs control the frequency and precise timing of spikes in neurons of the deep cerebellar nuclei (DCN). Although this technique is now widely used, it is limited to interpreting conductance inputs as being location independent; i.e.,(More)
Small conductance Ca2+-activated potassium (SK) current provides an important modulator of excitatory synaptic transmission, which undergoes plastic regulation via multiple mechanisms. We examined whether inhibitory input processing is also dependent on SK current in the cerebellar nuclei (CN) where inhibition provides the only route of information transfer(More)
Lin RJ, Jaeger D. Using computer simulations to determine the limitations of dynamic clamp stimuli applied at the soma in mimicking distributed conductance sources.vious studies we used the technique of dynamic clamp to study how temporal modulation of inhibitory and excitatory inputs control the frequency and precise timing of spikes in neurons of the deep(More)
Multi-barrelled micro-electrode has been used to observe further the effect of Li+ applied iontophoretically on electrical activities of pain related neurons (PRN) of the rat caudate-putamen nucleus (CPN) and its mechanism of action was studied at the cellular level. It was found that PRN were homogeneously distributed throughout the head of CPN, but(More)
Extracellular recordings were made in the nucleus paragigantocellularis (PGL) of the cat in response to stimulation of the hypothalamic perifornical defence area (HPDA), dorsal periaqueductal grey matter (PAG), nucleus raphe obscurus (Rob), deep peroneal nerve (DPN), and superficial peroneal nerve (SPN). Stimulation of the HPDA, dorsal PAG and SPN evoked(More)
  • 1