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  • Hervé Tettelin, Vega Masignani, +43 authors Claire M. Fraser
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2005 (First Publication: 27 September 2005)
  • The development of efficient and inexpensive genome sequencing methods has revolutionized the study of human bacterial pathogens and improved vaccine design. Unfortunately, the sequence of a singleContinue Reading
  • Stefano Censini, Christoph Lange, +5 authors Antonello Covacci
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1996 (First Publication: 10 December 1996)
  • cagA, a gene that codes for an immunodominant antigen, is present only in Helicobacter pylori strains that are associated with severe forms of gastroduodenal disease (type I strains). We found thatContinue Reading
  • Hervé Tettelin, Vega Masignani, +40 authors Claire M. Fraser
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2002 (First Publication: 28 August 2002)
  • The 2,160,267 bp genome sequence of Streptococcus agalactiae, the leading cause of bacterial sepsis, pneumonia, and meningitis in neonates in the U.S. and Europe, is predicted to encode 2,175 genes.Continue Reading
  • Francesco Dotta, Stefano Censini, +12 authors Piero Marchetti
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 2007 (First Publication: 20 March 2007)
  • Type 1 diabetes is characterized by T cell-mediated autoimmune destruction of pancreatic β cells. Several studies have suggested an association between Coxsackie enterovirus seroconversion and onsetContinue Reading
  • Elisabetta Traggiai, Stephan Becker, +6 authors Antonio Lanzavecchia
  • Biology, Medicine
  • Nature Medicine
  • 2004 (First Publication: 11 July 2004)
  • Passive serotherapy can confer immediate protection against microbial infection, but methods to rapidly generate human neutralizing monoclonal antibodies are not yet available. We have developed anContinue Reading
  • Z Xiang, Stefano Censini, +4 authors Antonello Covacci
  • Medicine, Biology
  • Infection and immunity
  • 1995
  • Colonization of the mucosa of the stomach and the duodenum by Helicobacter pylori is the major cause of acute and chronic gastroduodenal pathologies in humans. Duodenal ulcer formation stronglyContinue Reading