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  • R J Lund, Helena Ahlfors, Essi Kainonen, Anna-Maria Lahesmaa, Craig R. Dixon, Riitta Lahesmaa
  • Medicine, Biology
  • European journal of immunology
  • 2005 (First Publication: 1 November 2005)
  • The differentiation of naïve T helper (Th) cells is induced by TCR activation and IL-12/STAT4 or IL-4/STAT6 signaling pathways, forming Th1 and Th2 cells, respectively. In this study, oligonucleotideExpand
  • R. David Hawkins, Antti Larjo, +9 authors Riitta Lahesmaa
  • Biology, Medicine
  • Immunity
  • 2013 (First Publication: 27 June 2013)
  • Naive CD4⁺ T cells can differentiate into specific helper and regulatory T cell lineages in order to combat infection and disease. The correct response to cytokines and a controlled balance of theseExpand
  • R J Lund, Emmi K Ylikoski, Tero Aittokallio, Olli Nevalainen, Riitta Lahesmaa
  • Biology, Medicine
  • European journal of immunology
  • 2003 (First Publication: 1 April 2003)
  • Many genes implicated in Th1 and Th2 differentiation have been identified in both human and mouse. However, the functional roles and hierarchy of these factors in the signaling pathways leading toExpand