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USF1-induced upregulation of LINC01048 promotes cell proliferation and apoptosis in cutaneous squamous cell carcinoma by binding to TAF15 to transcriptionally activate YAP1
TLDR
Investigation of the biological role of a certain lncRNA in cutaneous squamous cell carcinoma found that YAP1, a Hippo pathway factor, was positively regulated by LINC01048, and mechanism investigation revealed that Linc01048 increased the binding of TAF15 to Yap1 promoter to transcriptionally activate YAP 1 in CSCC cells. Expand
Porcine acellular dermal matrix accelerates wound healing through miR-124-3p.1 and miR-139-5p.
TLDR
This work demonstrates that porcine ADM induced down-regulation of miR-124-3p.1/139-5p in wounds and up- regulation of JAG1/Notch1 in ESCs, thus enhancing cutaneous wound healing. Expand
Efficacy of fulguration combined with imiquimod cream on condyloma acuminatum, and the effect on immune functions and serums levels of IL-2 and IL-10
TLDR
Good efficacy can be achieved with the combined treatment of high-frequency fulguration and 5% imiquimod cream for CA, which is correlated with enhanced immune functions of T cells, and improvements in the serum levels of IL-2 and IL-10. Expand
Modulation effect of vaginal mucosal microflora and susceptibility to Neisseria gonorrhoeae infections: a systematic review and meta-analysis
TLDR
A systematic review and meta-analysis has demonstrated that LL-VMB was significantly associated with a high NG susceptibility, and could be regarded as worse prognostic factor. Expand
Effect of tea polyphenols on the growth of human papillomavirus 16 subgenes-immortalized human cervical epithelial cells
Objective To explore the effect of tea polyphenols on the growth of human papillomavirus 16 (HPV16) subgenes-immortalized human cervical epithelial cells (H8 cells) . Methods Cultured H8 cellsExpand