Ridha Hambli

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  • Ridha Hambli
  • Journal of the mechanical behavior of biomedical…
  • 2011
In this paper, a neural network model is developed to simulate the accumulation of apparent fatigue damage of 3D trabecular bone architecture at a given bone site during cyclic loading. The method is based on five steps: (i) performing suitable numerical experiments to simulate fatigue accumulation of a 3D micro-CT trabecular bone samples taken from(More)
Bone adaptation occurs as a response to external loadings and involves bone resorption by osteoclasts followed by the formation of new bone by osteoblasts. It is directly triggered by the transduction phase by osteocytes embedded within the bone matrix. The bone remodeling process is governed by the interactions between osteoblasts and osteoclasts through(More)
The purpose of this study was to develop a finite element model based on continuum damage mechanics in order to simulate the profile of the fractured area of proximal femur and the complete force-displacement curve from the beginning until complete fracture. The model was developed in term of anisotropic behaviour law coupled to quasi-brittle damage to(More)
Mineralized collagen microfibrils in human bone provide its mechanical properties (stiffness, elasticity, ductility, energy dissipation and strength). However, detailed 3D finite element models describing the mechanical behavior of the mineralized collagen microfibrils are still lacking. In the current work, we developed a 3D finite element model of the(More)
Most micro-CT finite element modeling of human trabecular bone has focused on linear and non-linear analysis to evaluate bone failure properties. However, prediction of the apparent failure properties of trabecular bone specimens under compressive load, including the damage initiation and its progressive propagation until complete bone failure into(More)
The purpose of this work was to develop an integrated remodeling-to-fracture finite element model allowing for the combined simulation of (i) simulation of a human proximal femur remodeling under a given boundary conditions, (ii) followed by the simulation of its fracture behavior (force-displacement curve and fracture pattern) under quasi-static load. The(More)
  • Ridha Hambli
  • Medical & Biological Engineering & Computing
  • 2012
In this paper, a simple and practical finite element (FE) model coupled to a quasi-brittle damage law to describe the initiation and progressive propagation of multiple cracks based on element deletion is developed to predict the complete force–displacement curve and the fracture pattern of a human proximal femur under quasi-static load. The motivation of(More)
The aim of this paper is to develop a multiscale hierarchical hybrid model based on finite element analysis and neural network computation to link mesoscopic scale (trabecular network level) and macroscopic (whole bone level) to simulate the process of bone remodelling. As whole bone simulation, including the 3D reconstruction of trabecular level bone, is(More)
The complexity and heterogeneity of bone tissue require a multiscale modeling to understand its mechanical behavior and its remodeling mechanisms. In this paper, a novel multiscale hierarchical approach including microfibril scale based on hybrid neural network (NN) computation and homogenization equations was developed to link nanoscopic and macroscopic(More)
Developing mathematical models describing the bone transduction mechanisms, including mechanical and metabolic regulations, has a clear practical applications in bone tissue engineering. The current study attempts to develop a plausible physiologically based mathematical model to describe the mechanotransduction in bone by an osteocyte mediated by the(More)