Rick P. Steeds

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BACKGROUND We assessed whether remote ischemic preconditioning (RIPC) improves myocardial, renal, and lung protection after on-pump coronary surgery. METHODS AND RESULTS This was a single-center, prospective, randomized (1:1), placebo-controlled trial. Patients, investigators, anesthetists, surgeons, and critical care teams were blinded to group(More)
BACKGROUND The association between depression after myocardial infarction and increased risk of mortality and cardiac morbidity may be due to cardiac disease severity. AIMS To combine original data from studies on the association between post-infarction depression and prognosis into one database, and to investigate to what extent such depression predicts(More)
Myocardial disease in systemic vasculitis and autoimmune disease detected by cardiovascular magnetic resonance SIR, Cardiovascular disease is a major cause of morbidity and mortality in patients with inflammatory autoimmune and vasculitic diseases such as systemic lupus erythematosus (SLE) and Wegener's granulomatosis (WG) [1, 2]. An increased prevalence of(More)
A 75-year-old man was referred to renal services in 2008 with a creatinine of 168 mmol/l and an estimated glomerular filtration rate (eGFR) of 35 ml/min/1.73 m 2. He had a past history of hyper-tension and carcinoma of the prostate previously treated with radiotherapy. There was no history of diabetes or cardiovascular disease. On referral, he was taking(More)
BACKGROUND Chronic kidney disease (CKD) is associated with accelerated cardiovascular disease and heart failure. Endothelial nitric oxide synthase (eNOS) Glu298Asp single nucleotide polymorphism (SNP) genotype has been associated with a worse phenotype amongst patients with established heart failure and in patients with progression of their renal disease.(More)
CONTEXT Uncertainty exists whether the long-term use of ergot-derived dopamine agonist (DA) drugs for the treatment of hyperprolactinemia may be associated with clinically significant valvular heart disease and whether current regulatory authority guidelines for echocardiographic screening are clinically appropriate. OBJECTIVE Our objective was to provide(More)
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