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Hemangiomas of infancy are the most common benign tumors of childhood. They are composed of proliferating endothelial tumor cells and usually manifest as cutaneous birthmarks. In most cases, these tumors characteristically follow a natural course of regression. However, they can cause a tremendous amount of anxiety. Hemangiomas can threaten vital life(More)
Desmethylperazine (norperazine) and desmethylprochlorperazine (norprochlorperazine), like nor1- and nor2chlorpromazine, are excellent substrates for indolethylamine N-methyltransferase (NMT) and also inhibit the formation of dimethyltryptamine (DMT) from N-methyl-tryptamine (NMT). Nortriptyline and protriptyline, antidepressant compounds which like NMT(More)
Cyclic Vomiting Syndrome (CVS) has been linked to episodic migraine, yet little is known about the precise brain-based mechanisms underpinning CVS, and whether these associated conditions share similar pathophysiology. We investigated the functional integrity of salience (SLN) and sensorimotor (SMN) intrinsic connectivity networks in CVS, migraine and(More)
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