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- Richelle C Prickett, Janet A W Elliott, Locksley E McGann
- Cryobiology
- 2010

The multisolute osmotic virial equation is the only multisolute thermodynamic solution theory that has been derived from first principles and can make predictions of multisolute solution behaviour in the absence of multisolute solution data. Other solution theories either (i) include simplifying assumptions that do not take into account the interactions… (More)

- Richelle C Prickett, Janet A W Elliott, Shamina Hakda, Locksley E McGann
- Cryobiology
- 2008

A non-ideal osmotic equilibrium equation is proposed as a replacement for the Boyle van't Hoff equation to describe the equilibrium volume of a living cell as a function of external osmolality. Contrary to common understanding, the Boyle van't Hoff equation is only thermodynamically correct for ideal, dilute solutions. However, the Boyle van't Hoff equation… (More)

- J A W Elliott, R C Prickett, H Y Elmoazzen, K R Porter, L E McGann
- The journal of physical chemistry. B
- 2007

The osmotic virial equation was used to predict osmolalities of solutions of interest in biology. The second osmotic virial coefficients, Bi, account for the interactions between identical solute molecules. For multisolute solutions, the second osmotic virial cross coefficient, Bij, describes the interaction between two different solutes. We propose to use… (More)

- Richelle C Prickett, Janet A W Elliott, Locksley E McGann
- The journal of physical chemistry. B
- 2011

The prediction of multisolute solution behavior of solutions containing electrolytes is important in many areas of research, including cryopreservation. In this study, the use of a novel form of the osmotic virial equation for multisolute solutions containing an electrolyte is investigated and compared to a rigorous electrolyte solution theory, the… (More)

- Richelle C Prickett, Leah A Marquez-Curtis, Janet A W Elliott, Locksley E McGann
- Cryobiology
- 2015

Intracellular ice formation (IIF) has been linked to death of cells cryopreserved in suspension. It has been assumed that cells can be supercooled by 2 to 10°C before IIF occurs, but measurements of the degree of supercooling that cells can tolerate are often confounded by changing extracellular temperature and solutions of different osmolality (which… (More)

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