Richard WJ Lee

Learn More
The eye, as currently viewed, is neither immunologically ignorant nor sequestered from the systemic environment. The eye utilises distinct immunoregulatory mechanisms to preserve tissue and cellular function in the face of immune-mediated insult; clinically, inflammation following such an insult is termed uveitis. The intra-ocular inflammation in uveitis(More)
  • Andrea L Kritcher, Paul Neumayer, John Castor, Tilo Döppner, Roger W Falcone, Otto L Landen +7 others
  • 2008
Spectrally resolved scattering of ultrafast K-alpha x-rays has provided experimental validation of the modeling of the compression and heating of shocked matter. The elastic scattering component has characterized the evolution and coalescence of two shocks launched by a nanosecond laser pulse into lithium hydride with an unprecedented temporal resolution of(More)
BACKGROUND Acute maculopathy is a rare condition of unknown aetiology and Coxsackie virus is known to be associated with this macular chorioretinitis. FINDINGS We report a case of acute unilateral maculopathy in a 35-year-old woman with concurrent hand foot and mouth disease. Furthermore, we display multimodal imaging (colour fundus photographs,(More)
Uveitis, a group of conditions characterized by intraocular inflammation, is a major cause of sight loss in the working population. Most uveitis seen in Western countries is noninfectious and appears to be autoimmune or autoinflammatory in nature, requiring treatment with immunosuppressive and/or anti-inflammatory drugs. In this educational review, we(More)
BACKGROUND Medical management of thyroid eye disease remains controversial due to a paucity of high quality evidence on long-term treatment outcomes. Glucocorticoids are known to be effective initially but have significant side-effects with long-term use and recrudescence can occur on cessation. Current evidence is conflicting on the efficacy of(More)
The beginnings of the 5-D analysis methodology lie in research by Robert Cervero 1. This original research found that certain characteristics of the neighborhood around a household affected the number of vehicle trips and vehicle-miles traveled generated by that household. This effect was independent of household characteristics (income, household size,(More)
Research has suggested that prenatal depression may be associated with disrupted maternal responses to infant stimuli, with depressed pregnant women not showing the bias toward distressed infants as that observed in nondepressed pregnant women. The current study examined the effects of depression on self- reported responses to infant stimuli, in early(More)
We have developed a method to label and image myeloid cells infiltrating the mouse retina and choroid in vivo, using a single depot injection of indocyanine green dye (ICG). This was demonstrated using the following ocular models of inflammation and angiogenesis: endotoxin-induced uveitis, experimental autoimmune uveoretinitis and laser-induced choroidal(More)
  • 1