Richard W. Hertle
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Leber's congenital amaurosis (LCA) is a group of inherited blinding diseases with onset during childhood. One form of the disease, LCA2, is caused by mutations in the retinal pigment… Continue Reading
Idiopathic congenital nystagmus is characterized by involuntary, periodic, predominantly horizontal oscillations of both eyes. We identified 22 mutations in FRMD7 in 26 families with X-linked… Continue Reading
OBJECTIVE To evaluate the effectiveness of treatment of amblyopia in children aged 7 to 17 years. METHODS At 49 clinical sites, 507 patients with amblyopic eye visual acuity ranging from 20/40 to… Continue Reading
OBJECTIVE To compare 2 hours vs 6 hours of daily patching as treatments for moderate amblyopia in children younger than 7 years. METHODS In a randomized multicenter (35 sites) clinical trial, 189… Continue Reading
PURPOSE To report a computerized method for determining visual acuity in children using the Amblyopia Treatment Study visual acuity testing protocol. METHODS A computerized visual acuity tester was… Continue Reading
OBJECTIVE We wished to determine the effectiveness of horizontal rectus tenotomy in changing the nystagmus of patients with congenital nystagmus and, secondarily, how their visual function changed.… Continue Reading
OBJECTIVE To evaluate the reliability of a new visual acuity testing protocol for children using isolated surrounded HOTV optotypes. METHODS After initial pilot testing and modification, the… Continue Reading
Involuntary occular oscillations in infancy and childhood can be understood, diagnosed, classified and treated as a result of modern electrophysiology and neuroanatomical knowledge.
PURPOSE We report a new method of measuring visual function in patients with INS by demonstrating the effects of eccentric gaze and forced time restriction on optotype recognition. DESIGN… Continue Reading
Background/aims: The infantile nystagmus syndrome (INS) usually begins in infancy and may or may not be associated with visual sensory system abnormalities. Little is known about its specific… Continue Reading