Richard W. Barnett

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  • M Y Ma, L S Reid, +4 authors R W Barnett
  • 1993
Double-stranded oligodeoxyribonucleotides or single-stranded oligoribonucleotides with specific secondary structure have been proposed as potential antagonists to target nucleic acid-binding proteins (the sense approach). A major limitation of this strategy is that these derivatives are generally considered to be too large for pharmaceutical applications.(More)
Transactivation of human immunodeficiency virus (HIV) gene expression requires binding of the viral Tat protein to a RNA hairpin-loop structure (TAR) which contains a two or three-nucleotide bulge. Tat binds in the vicinity of the bulge and the two adjacent duplex stems, recognising both specific sequence and structural features of TAR. Binding is mediated(More)
The glycoprotein hormones are a family of alpha beta heterodimeric proteins which are responsible for gonadal and thyroid function. In previous studies we employed chimeric glycoprotein hormone beta-subunits to identify amino acid residues critical for binding to receptors and antibodies. To facilitate similar studies of the alpha-subunit of these hormones,(More)
A step-wise discriminant function analysis identified demographic, personality, and intellectual variables that differentiate categories of felony offenders. Male inmates (N = 766) were categorized according to their most recent offense (Person, Property, Drug, or Indecent Liberties). Each completed the 16PF and the Multidimensional Aptitude Battery. A(More)
The Millon Clinical Multiaxial Inventory (MCMI) is a recently introduced instrument designed to measure both symptomatology and long-standing patterns of personality disorder in clinical populations. Because it is designed to assess clients who are similar to those with whom the MMPI is often used (e.g., adjudicated offenders), a question may arise as to(More)
A multiple regression analysis was used to determine the susceptibility of the 16 Personality Factor Test (16PF) to faking for a sample of male felons. The study is a replication of an earlier study of a similar sample. Motivational distortion (MD) correlated significantly with the 16PF primary scores. The relationship was most evident when the structure(More)
The 16 PF scores for 678 male offenders in a diagnostic and receiving center were compared with scores for 891 male offenders in penal institutions by t tests for independent means. Significant differences were obtained for 13 of the 16 primaries included in the 16 PF. The Penitentiary group scored significantly higher than the Reception Center group on the(More)
A series of tables were created to examine the phenomenon of the overrepresentation of verbal/performance splits among incarcerated felons. Multidimensional Aptitude Battery (MAB; Jackson, 1984) scores were obtained for 1,225 adult male felons referred to a reception and diagnostic center for evaluation. The findings suggest that there is a significant,(More)
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