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  • William R. Parrish, Mauricio Rosas-Ballina, +14 authors Valentin A Pavlov
  • Biology, Medicine
  • Molecular medicine
  • 2008 (First Published: 1 September 2008)
  • The α7 subunit-containing nicotinic acetylcholine receptor (α7nAChR) is an essential component in the vagus nerve-based cholinergic anti-inflammatory pathway that regulates the levels of TNF, highContinue Reading
  • Jared M. Huston, Margot Gallowitsch-Puerta, +12 authors Kevin J Tracey
  • Medicine
  • Critical care medicine
  • 2007 (First Published: 1 December 2007)
  • OBJECTIVE Electrical vagus nerve stimulation inhibits proinflammatory cytokine production and prevents shock during lethal systemic inflammation through an alpha7 nicotinic acetylcholine receptorContinue Reading
  • Mauricio Rosas-Ballina, Richard S. Goldstein, +7 authors Kevin J Tracey
  • Biology, Medicine
  • Molecular medicine
  • 2009 (First Published: 1 July 2009)
  • The cholinergic antiinflammatory pathway modulates Inflammatory cytokine production through a mechanism dependent on the vagus nerve and the α7 subunit of the nicotinic acetylcholine receptor. GTS-21Continue Reading
  • Richard S. Goldstein, Annette Bruchfeld, +11 authors Kevin J Tracey
  • Medicine
  • Molecular medicine
  • 2007 (First Published: 1 March 2007)
  • High Mobility Group Box-1 (HMGB1) is a cytokine implicated in the pathogenesis of rheumatoid arthritis (RA) and other inflammatory diseases. The cholinergic anti-inflammatory pathway, a vagusContinue Reading