Richard Rodriguez

Learn More
Although regeneration is widespread among metazoa, the molecular mechanisms have been studied in only a handful of taxa. Of these taxa, fewer still are amenable to studies of embryogenesis. Our understanding of the evolution of regeneration, and its relation to embryogenesis, therefore remains limited. Using β-catenin as a marker, we investigated the role(More)
Purpose: To evaluate the pharmacologic activity of a novel inhibitor of IkB kinase b (IKK2), LY2409881, in preclinical models of Band T-cell lymphoma, as a single agent and in combination with histone deacetylase (HDAC) inhibitors. Experimental Design: The in vitro activity of LY2409881 was determined using an ATP-based growth inhibition assay and flow(More)
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. ● Word count of the Main Text excluding references and figure legends: 6502. ● Total number of figures and tables: 5 figures and 1 table. ● Supplementary Data are uploaded, including 3 tables. Author manuscripts have been peer reviewed and accepted for(More)
  • 1