Richard Pebody

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OBJECTIVE To establish mortality from pandemic A/H1N1 2009 influenza up to 8 November 2009. DESIGN Investigation of all reported deaths related to pandemic A/H1N1 in England. SETTING Mandatory reporting systems established in acute hospitals and primary care. PARTICIPANTS Physicians responsible for the patient. MAIN OUTCOME MEASURES Numbers of(More)
Coronaviruses have the potential to cause severe transmissible human disease, as demonstrated by the severe acute respiratory syndrome (SARS) outbreak of 2003. We describe here the clinical and virological features of a novel coronavirus infection causing severe respiratory illness in a patient transferred to London, United Kingdom, from the Gulf region of(More)
†Maria D Van Kerkhove1,2 Katelijn AH Vandemaele1, Vivek Shinde1, Giovanna Jaramillo-Gutierrez,1 Artemis Koukounari,2 Christl Donnelly,2 Luis O. Carlino,3 Rhonda Owen,4 Beverly Paterson,4 Louise Pelletier,5 Julie Vachon,5 Claudia Gonzalez,6 Yu Hongjie,7 Feng Zijian,7 Shuk Kwan Chuang,8 Albert Au,8 Silke Buda,9 Gerard Krause,9 Walter Haas,9 Isabelle(More)
The 2011/12 season was characterised by unusually late influenza A (H3N2) activity in the United Kingdom (UK). We measured vaccine effectiveness (VE) of the 2011/12 trivalent seasonal influenza vaccine (TIV) in a test-negative case–control study in primary care. Overall VE against confirmed influenza A (H3N2) infection, adjusted for age, surveillance scheme(More)
BACKGROUND 18,500 laboratory-confirmed deaths caused by the 2009 pandemic influenza A H1N1 were reported worldwide for the period April, 2009, to August, 2010. This number is likely to be only a fraction of the true number of the deaths associated with 2009 pandemic influenza A H1N1. We aimed to estimate the global number of deaths during the first 12(More)
Human monkeypox, a sporadic smallpox-like zoonotic viral exanthema that occurs in the rain forests of Central and West Africa, was discovered in 1970 (1-3). The illness is caused by an orthopoxvirus, monkeypox virus, which was first isolated from primate tissues (4). Animal antibody surveys in the Democratic Republic of Congo (DRC; former Zaire) suggested(More)
OBJECTIVES To describe the seroepidemiology of herpes simplex virus (HSV) types 1 and 2 in the general populations of eight European countries to better understand recent reported changes in disease epidemiology. METHODS Belgium, Bulgaria, Czech Republic, England and Wales, Finland, Germany, Netherlands, and Slovenia conducted national cross sectional(More)
R G Pebody (, F Warburton1, J Ellis2, N Andrews1, C Thompson2, B von Wissmann3, H K Green1, S Cottrell4, J Johnston5, S de Lusignan6, C Moore7, R Gunson8, C Robertson9,10, J McMenamin3, M Zambon2 1. Public Health England Centre of Infectious Disease Surveillance and Control, London, United Kingdom 2. Public Health England(More)
Seven countries in Western Europe collected large, representative serum banks across the entire age range and tested them for diphtheria anti-toxin (sample size ranged from 2991 to 7715). Although a variety of assays were used, the results were all standardized to those of a reference laboratory and expressed in international units. The standardization(More)
A 10-month longitudinal household study of pre-school children and their families was undertaken with monthly visits collecting epidemiological data and nasopharyngeal swabs in Hertfordshire, England from 2001 to 2002. Pneumococcal culture was with standard methods. In total, 121 families (489 individuals) took part. Mean prevalence of carriage ranged from(More)