Richard Patrick White

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Many investigators have concluded that hemoglobin is the spasmogen responsible for cerebral vasospasm. The present study was designed to ascertain whether the contractile responses of isolated canine basilar arteries to xanthochromic cerebrospinal fluid from subarachnoid hemorrhage patients was associated with hemoglobin concentration as measured(More)
DESCRIPTION A 48-year-old previously healthy woman presented with a 1-month history of increasing clumsiness, ataxia, bilateral swaying while walking with frequent falls and a 20-day history of slurred speech, difficulty swallowing and nasal regurgitation. There was no recent decline in memory, no seizures and no blurred vision. A CT scan of the brain(More)
Introduction. The hyperdense internal carotid artery sign (HICAS) has been suggested as a common marker of terminal internal carotid artery (ICA) thrombus associated with poor outcomes following thrombolysis. We aimed to investigate the prevalence and prognostic significance of the HICAS in an unselected cohort of patients receiving intravenous(More)
BACKGROUND The validity of the clinical dictum "the presence of spontaneous retinal venous pulsation (SVP) excludes raised intracranial pressure" has not been previously tested. We set out to determine the specificity and positive predictive value (PPV) of the presence of SVP to indicate normal intracranial pressure (ICP) in a routine clinical setting. (More)
Midazolam is a new, water-soluble benzodiazepine that has been reported to produce a greater degree of amnesia than does diazepam. This study compares the amnesia produced in patients sedated with midazolam or diazepam or in combination with fentanyl during oral surgery. Twenty-four hours after surgery, each patient answered a questionnaire designed to(More)
BACKGROUND The impact of circle of Willis anatomical variation upon the presentation of stroke is probably underrecognized. CASE PRESENTATION A 63-year-old right-handed woman developed a left hemiparesis and right leg weakness sequentially following a road traffic accident (RTA). Despite initial concern about the possibility of cervical spinal cord(More)