Richard P Sorelle

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BACKGROUND The Department of Health and Human Services recently called for public comment on human subjects research protections. OBJECTIVE To assess variability in reviews across institutional review boards (IRBs) for a multisite, minimal-risk trial of financial incentives for evidence-based hypertension care and to quantify the effect of review(More)
Human chromosome 12 contains more than 1,400 coding genes and 487 loci that have been directly implicated in human disease. The q arm of chromosome 12 contains one of the largest blocks of linkage disequilibrium found in the human genome. Here we present the finished sequence of human chromosome 12, which has been finished to high quality and spans(More)
OBJECTIVES To examine the impact of financial incentives on physician goal commitment to guideline-recommended hypertension care. STUDY DESIGN Clinic-level cluster-randomized trial with 4 arms: individual, group, or combined incentives, and control. METHODS A total of 83 full-time primary care physicians at 12 Veterans Affairs medical centers completed(More)
The problem of orphaned and abandoned children with AIDS living in Romania is examined. The threadbare existence of these children is depicted in descriptions and pictures. Romania is home to more than one-half of the children with AIDS in Europe and charitable donations and efforts are decreasing. The history of how this occurred is outlined, including(More)
Increasing numbers of research studies test interventions for clinicians in addition to or instead of interventions for patients. Although previous studies have enumerated barriers to patient enrolment in clinical trials, corresponding barriers have not been identified for enrolling clinicians as subjects. We propose a framework of metrics for(More)
BACKGROUND Given the increase in financial-incentive programs nationwide, many physicians and physician groups are concerned about potential unintended consequences of providing financial incentives to improve quality of care. However, few studies examine whether actual unintended consequences result from providing financial incentives to physicians. We(More)
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