Richard P. Long

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Severe Combined Immune Deficiency (SCID) is universally fatal unless treated with hematopoietic stem cell transplantation (HSCT). Following the identification of disseminated Bacille Calmette-Guérin (BCG) infections in Canadian First Nations, Métis and Inuit (FNMI) children with unrecognized primary immune deficiencies, a national surveillance study was(More)
Patterns of gene flow can have marked effects on the evolution of populations. To better understand the migration dynamics of Mycobacterium tuberculosis, we studied genetic data from European M. tuberculosis lineages currently circulating in Aboriginal and French Canadian communities. A single M. tuberculosis lineage, characterized by the DS6(Quebec)(More)
Beijing strains are speculated to have a selective advantage over other Mycobacterium tuberculosis strains because of increased transmissibility and virulence. In Alberta, a province of Canada that receives a large number of immigrants, we conducted a population-based study to determine whether Beijing strains were associated with increased transmission(More)
This study evaluated drivers' behavior in yielding the right-of-way to sighted and blind pedestrians who stood at different stopping distances from the crosswalk lines at entry and exit lanes at two different roundabouts. The findings demonstrate that drivers' willingness to yield to pedestrians is affected by whether they are attempting to cross at the(More)
SETTING Nationwide Canadian public health surveillance. OBJECTIVE Description of demographic features and disease characteristics of drug-resistant tuberculosis (TB) in Canada over a 12 year period. DESIGN Continuous surveillance of all cases of culture-confirmed TB in Canada. Demographic and microbiologic features were analyzed and comparisons between(More)
STRaND-1 is the first in a series of Surrey Satellite Technology Ltd. (SSTL)-Surrey Space Centre (SSC) collaborative satellites designed for the purpose of technology path finding for future commercial operations. It is the first time Surrey has entered the CubeSat field and differs from most CubeSats in that it will fly a modern Commercial Off The Shelf(More)
INTRODUCTION Compliance with the recommendation that all tuberculosis (TB) patients be tested for human immunodeficiency virus (HIV) has not yet been achieved in Canada or globally. METHODS The experience of "opt-out" HIV testing of TB patients in the Province of Alberta, Canada is described over a 10-year period, 2003-2012. Testing rates are reported(More)
INTRODUCTION Mycobacterium tuberculosis Beijing strains are frequently associated with tuberculosis outbreaks and drug resistance. However, contradictory evidence and limited study generalizability make it difficult to foresee if the emergence of Beijing strains in high-income immigrant-receiving countries poses an increased public health threat. The(More)
RATIONALE Treatment for latent tuberculosis infection with isoniazid for 9 months (9INH) has poor completion and serious adverse events, while treatment for 4 months with daily rifampin (4RIF) has significantly higher completion and fewer adverse events. OBJECTIVES To compare the health system costs of 4RIF and 9INH. METHODS In a randomised trial(More)
INTRODUCTION Tuberculosis (TB) is now a relatively uncommon disease in high income countries. As such, its diagnosis may be missed or delayed resulting in death before or shortly after the introduction of treatment. Whether early TB death is associated with increased TB transmission is unknown. To determine the transmission risk attributable to early TB(More)