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Despite recent progress in anti-human immunodeficiency virus (HIV) therapy, drug toxicity and emergence of drug-resistant isolates during long-term treatment of HIV-infected patients necessitate the search for new targets that can be used to develop novel antiviral agents. One such target is the process of nuclear translocation of the HIV preintegration(More)
BACKGROUND Pre-eclampsia/eclampsia is one of the most common causes of maternal and perinatal morbidity and mortality in low and middle income countries. Magnesium sulfate is the drug of choice for prevention of seizures as part of comprehensive management of the disease. Despite the compelling evidence for the effectiveness of magnesium sulfate, concern(More)
1. The availability of lysine in seven vegetable protein concentrates was determined using the slope-ratio assay with growing pigs and rats and with two chemical techniques. 2. With pigs, estimates of availability were lower using carcass compared to live-weight values, but there was no consistent effect of including food intake in the criterion of(More)
  • R F Lowe
  • 1970
Shallowness of the anterior chamber received special attention after the demonstration by von Graefe (1857) that iridectomy could cure acute glaucoma. Bowman (I862) referred to the care required in performing iridectomies on eyes with shallow anterior chambers. Over many years, and by careful dissections of cadaver and enucleated eyes, Priestley Smith(More)
Electropermeabilization is a method that uses electric field pulses to induce an electrically mediated reorganization of the plasma membrane of cells. Electrochemotherapy combines local or systemic administration of chemotherapeutic drugs such as bleomycin or cisplatin that have poor membrane permeability with electropermeabilization by direct application(More)
  • R F Lowe
  • 1972
The picture of primary angle-closure glaucoma accompanied by its shallow anterior chamber is so distinct that for many years it has evoked considerable curiosity concerning possible genetic determination. Family trees were published (Sedan and Sedan-Bauby, 1949; Waardenburg, I96I) and attempts were made to fit the inheritance into a genetic pattern-but(More)