Richard Love

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Breast cancer (BC) patients need traditional treatment as well as long term monitoring through an adaptive feedback-oriented treatment mechanism. Here, we present the findings of our 31-week long field study and deployment of e-ESAS - the first mobile-based remote symptom monitoring system (RSMS) developed for rural BC patients where patients are the prime(More)
Postmenopausal women with breast cancer in remission (N = 140) who were participating in a randomized clinical trial of tamoxifen chemoprevention therapy completed measures of trait anxiety, symptoms, cancer worry, and breast self-examinations (BSEs) during the first 6 months of the trial. Trait anxiety was associated with heightened sensitivity to(More)
Women in low- and middle-income countries (LMICs) have yet to benefit from recent advances in breast cancer diagnosis and treatment now experienced in high-income countries. Their unique sociocultural and health system circumstances warrant a different approach to breast cancer management than that applied to women in high-income countries. Here, we present(More)
Healthcare facility is scarce for rural women in the developing world. The situation is worse for patients who are suffering from diseases that require long-term feedback-oriented monitoring such as breast cancer. Lack of motivation to go to the health centers on patients’ side due to sociocultural barriers, financial restrictions and transportation hazards(More)
BACKGROUND While tamoxifen activity is mainly due to endoxifen and the concentration of this active metabolite is, in part, controlled by CYP2D6 metabolic status, clinical correlative studies have produced mixed results. FINDINGS In an exploratory study, we determined the CYP2D6 metabolic status and plasma concentrations of endoxifen among 224 Filipino(More)
In this paper, we present e-ESAS, a mobile phone based remote monitoring tool for patients with palliative care need, carefully designed for developing countries. Most of the current remote monitoring systems are complex, obtrusive and expensive resulting in a system unsuitable to deploy in low-income countries. We here describe evolution and performance of(More)
The growing burden of non-communicable diseases including cancer in low- and lower-middle income countries (LMICs) and in geographic-access limited settings within resource-rich countries requires effective and sustainable solutions. The International Cancer Expert Corps (ICEC) is pioneering a novel global mentorship-partnership model to address workforce(More)
OBJECTIVE Tamoxifen therapy preserves BMD of the lumbar spine and increases levels of SHBG. We assessed whether trait anxiety, a factor linked with a reactive endocrine system, is associated with differential changes in BMD and SHBG levels in response to tamoxifen therapy. METHODS Postmenopausal women (N= 140) with axillary-node-negative breast cancer(More)
Timely and accurate information about patients' symptoms is important for clinical decision making such as adjustment of medication. Due to the limitations of self-reported symptom such as pain, we investigated whether facial images can be used for detecting pain level accurately using existing algorithms and infrastructure for cancer patients. For low cost(More)