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An ongoing outbreak of exceptionally virulent Shiga toxin (Stx)-producing Escherichia coli O104:H4 centered in Germany, has caused over 830 cases of hemolytic uremic syndrome (HUS) and 46 deaths since May 2011. Serotype O104:H4, which has not been detected in animals, has rarely been associated with HUS in the past. To prospectively elucidate the unique(More)
Genome sequencing with next-generation sequence (NGS) technologies can now be applied to organisms pivotal to addressing fundamental biological questions, but with genomes previously considered intractable or too expensive to undertake. However, for species with large and complex genomes, extensive genetic and physical map resources have, until now, been(More)
The Trestles system is targeted to modest-scale and gateway users, and is designed to enhance users' productivity by maintaining good turnaround time as well as other user-friendly features such as long run times and user reservations. However, the goal of maintaining good throughput competes with the goal of high system utilization. This paper analyzes one(More)
A commentary on The icmF3 locus is involved in multiple adaptation-and virulence-related characteristics in Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa is an important pathogen commonly isolated from patients with burns, wounds and cystic fibrosis (Lyczak et al., 2000; Gellatly and Hancock, 2013). The P. aeruginosa strain PAO1 was originally reported(More)
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