Richard L Mones

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This article intends to test the hypothesis that gamma-glutamyl transferase (GGT) may be used as a reliable marker to distinguish skeletal muscle damage from liver damage in Duchenne muscular dystrophy (DMD) patients. To demonstrate this, the authors compare the levels of creatine kinase (CK) and GGT, at 2 different points during the day, in 28 subjects(More)
OBJECTIVE The objective of this study was to investigate the effect of chronic constipation on children's quality of life. METHODS From October 2002 to November 2003, 224 children (140 male, 84 female, aged 10.6 +/- 2.9 years) and 224 parents were evaluated by a health related quality of life tool during initial outpatient consultation. Children with(More)
BACKGROUND AND AIMS The "gold standard" for the diagnosis of celiac disease (CD) is the small intestinal biopsy. A significant number of biopsies are inadequate for interpretation. Furthermore, the labeling of a biopsy as a Marsh I or II is somewhat subjective and may vary with the experience of the pathologist. Our hypothesis is that patients with intact(More)
OBJECTIVE The aim of this study was to assess the efficacy of a cognitive-behavioral approach to the treatment of recurrent abdominal pain caused by childhood functional gastrointestinal disorders (FGIDs). METHODS From September 2001 to December 2002, 18 patients (12 male; mean age, 12.1 +/- 4.9 years) with chronic abdominal pain (mean duration, 11.8 +/-(More)
Ascending cholangitis after portoenterostomy for biliary atresia often leads to significant morbidity. The long-term prognosis also involves recurrent and frequently recalcitrant bouts of cholangitis. Attempts at prophylaxis with use of oral antibiotics are frequently unsuccessful. The authors describe three patients who, after successful(More)
Infant colic is an extremely common but poorly understood symptom complex, causing great distress for infant, parents, and physician. Many theories have been suggested to explain this entity, but none are widely accepted. Numerous therapies have been proposed; however, few are helpful. A review of infant colic is presented which focuses on suggested(More)
There are many extra-intestinal manifestations of inflammatory bowel disease (IBD), some which are very uncommon in the pediatric age group. Coagulation abnormalities occur infrequently. Both hypercoagulability and hypocoagulability have been reported in adults (1). The hypercoagulable state is reflected in a general increase in concentration of clotting(More)