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Journals and Conferences
OBJECTIVES The efficacy of multidrug intravenous sedation regimens in oral surgery is based on the ability to titrate opioids, benzodiazepines, and barbiturates to a desired level of relaxation. Dosage requirements to reach the initial sedation end points of slurred speech and ptosis of eyelids vary widely from one patient to another. STUDY DESIGN An… (More)
This double-blind, controlled clinical trial assessed the anxiety relief provided by oral triazolam given before intravenous sedation. Twenty-two healthy adults undergoing third-molar surgery with intravenous sedation were enrolled in this study. Subjects were randomly assigned to receive either 0.25 mg of triazolam p.o. or an identically appearing placebo… (More)
A dentist's ability to safely administer regional anesthesia is essential for dental practice. Local anesthetic solutions used in the United States for dental anesthesia are formulated with several components. The contents of a standard local anesthetic cartridge may include an amide or ester local anesthetic drug, an adrenergic vasoconstrictor, and an… (More)
The addition of a benzodiazepine antagonist to the dental anesthesiologist's armamentarium should provide added safety for conscious sedation using benzodiazepines. A double-blind, placebo-controlled clinical trial of flumazenil, the first available benzodiazepine antagonist, was performed to evaluate its safety and efficacy following conscious sedation… (More)
This article defines the specific situations in which pharmacologic management and treatment of dental anxiety are appropriate and the services of a dentist anesthesiologist are required.
Benzodiazepines, including diazepam and midazolam, have proved to be safe and effective for intravenous conscious sedation. Their selective anxiolytic activity and wide margin of safety contribute to their popularity. The recent introduction of the benzodiazepine receptor antagonist, flumazenil, provides flexibility and added safety for intravenous… (More)
The case reported is typical of narcotic overdose. The sequence of events, however, is predictable when narcotics are administered in excess. Effective monitoring and the use of emergency equipment can prevent a fatality.
A review of the English literature on the pharmacologic effects of scopolamine is presented and indications for the current use of the drug in dental anesthesia and analgesia are evaluated. The authors conclude that the role of scopolamine in the production of conscious sedation for outpatient dental surgery should be reevaluated in the light of… (More)