Mechanisms underlying age-related defects within lymphoid-lineages remain poorly understood. We previously reported that sex steroid ablation (SSA) induced lymphoid rejuvenation and enhanced recovery from hematopoietic stem cell (HSC) transplantation (HSCT). We herein show that, mechanistically, SSA induces hematopoietic and lymphoid recovery by… (More)
Thymic epithelial cells (TECs) play a critical role in T cell maturation and tolerance induction. The generation of TECs from in vitro differentiation of human pluripotent stem cells (PSCs) provides a platform on which to study the mechanisms of this interaction and has implications for immune reconstitution. To facilitate analysis of PSC-derived TECs, we… (More)
characterisation and applicability of a monoclonal antibody to hybrid surubim catfish Pseudoplatystoma corruscans (Agassiz) x Pseudoplatystoma fasciatum (Linnaeus) immunoglobulin. A.J. 2004. Production and characterization of a putative T-cell marker in hybrid Surubin catfish Pseudoplatystoma corruscans (Agassiz) x Pseudoplatystoma fasciatum (Linnaeus).