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BACKGROUND It is uncertain how best to screen pregnant women for the presence of fetal Down's syndrome: to perform first-trimester screening, to perform second-trimester screening, or to use strategies incorporating measurements in both trimesters. METHODS Women with singleton pregnancies underwent first-trimester combined screening (measurement of nuchal(More)
OBJECTIVE To determine if first trimester fetal growth is associated with birth weight, duration of pregnancy, and the risk of delivering a small for gestational age infant. DESIGN Prospective cohort study of 38 033 pregnancies between 1999 and 2003. SETTING 15 centres representing major regions of the United States. PARTICIPANTS 976 women from the(More)
Sexual size dimorphism is thought to contribute to the greater mortality and morbidity of men compared with women. However, the timing of onset of sexual size dimorphism remains uncertain. The authors determined whether human fetuses exhibit sexual size dimorphism in the first trimester of pregnancy. Using a prospective cohort study, conducted in 1999–2002(More)
On behalf of the American Congress of Obstetricians and Gynecologists (ACOG), District II we are pleased to provide you with the second chapter of the Optimizing Protocols in Obstetrics series. While the first chapter addressed the use of oxytocin for induction, this chapter's content focuses on the Management of Obstetric Hemorrhage. Twenty three existing(More)
factors were integrated into a CRS ranging from 0–16. Predicted probability of SSM associated with each risk score was estimated. Predicted and observed risks of SSM were highly comparable. ConClusion: We present a validated risk stratification tool for predicting 30-day SSM following reduction mam-moplasty using data that are readily available to the(More)
The current mechanism for obtaining financial support for families with neurologically impaired infants is seriously flawed. It relies on payment awarded through the tort system based on a claim that medical negligence was responsible for the infant's condition. The system is extraordinarily inefficient and expensive, as well as being unfair to many(More)
Great advances in ultrasound instrumentation have enabled the physician to delineate subtle intrauterine changes. Not only can specific measurements of the fetal body be obtained but tissue textures within fetal organs can be appreciated. The perinatologist is constantly searching for ways to learn more about the fetus, and ultrasound has clearly become a(More)
463 amines. In the early 1960's, Hillarp, Falck, and their co-workers developed the basic technique for visualizing amine-containing neurons. Treating freeze-dried tissue sections with dry formaldehyde vapor brings about condensation of the amino group of the biogenic amines with the formaldehyde. A new conjugated ring is formed, and the product fluoresces(More)
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