Richard Kennedy

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OBJECTIVE To outline the diagnosis and management of intralabyrinthine schwannomas and to propose a new classification system to further define them. STUDY DESIGN Retrospective case review. SETTING Tertiary referral center at a university hospital. PATIENTS Twenty-eight patients seen at the institution with intralabyrinthine schwannomas between 1996(More)
PURPOSE To describe the clinical features of and identify the disease-causing mutation in a large Utah family segregating a dominantly inherited syndrome of optic atrophy, sensorineural hearing loss, ptosis, and ophthalmoplegia. DESIGN Observational case series. METHODS Thirty individuals at risk for a syndrome of optic atrophy, sensorineural hearing(More)
The aim of this study was to determine which, and how many, data items are required to construct a decision support algorithm for early diagnosis of acute myocardial infarction using clinical and electrocardiographic data available at presentation. Logistic regression models were derived using data items from 600 consecutive patients at one centre(More)
OBJECTIVE To derive statistical models for the diagnosis of acute coronary syndromes by using clinical and ECG information at presentation and to assess performance, portability, and calibration of these models, as well as how they may be used with cardiac marker proteins. DESIGN AND METHODS Data from 3462 patients in four UK teaching hospitals were used.(More)
BACKGROUND AND PURPOSE ILS is a rare lesion that has a different management from the more common "acoustic" schwannoma. To date, only 137 cases have been reported. We present a classification scheme based on labyrinthine anatomy to describe and localize these lesions. Treatment and prognosis hinge on the appropriate localization of these tumors; thus, a(More)
Recent studies have confirmed that artificial neural networks (ANNs) are adept at recognising patterns in sets of clinical data. The diagnosis of acute myocardial infarction (AMI) in patients presenting with chest pain remains one of the greatest challenges in emergency medicine. The aim of this study was to evaluate the performance of an ANN trained to(More)
OBJECTIVE To compare the effectiveness of two stapes prostheses in hearing improvement of patients undergoing stapes surgery for otosclerosis. STUDY DESIGN Retrospective chart review. METHODS Titanium and Teflon wire stapes prostheses were compared with regard to effectiveness in closing the air-bone gap. The charts of 461 stapedectomies performed by(More)
Fatty acids (FAs) are important as metabolic substrates and as structural components of biological membranes. However, they also function as signalling molecules. Recently, a series of G protein-coupled receptors (GPRs) for FAs has been described and characterized. These receptors have differing specificities for FAs of differing chain length and degree of(More)
The accurate determination of gastric emptying time requires correction or compensation for tissue attenuation. The gold standard for tissue attenuation correction for gastric emptying is the geometric mean of the gastric counts from the anterior and posterior views. For reasons of efficiency, many community hospitals acquire only the anterior projection.(More)