Richard K. Cho

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Polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes syndrome is a rare multisystem disorder. Overproduction of vascular endothelial growth factor (VEGF) by plasmocytoma could be responsible for the symptoms. The authors treated four patients with high-dose chemotherapy and autologous peripheral blood stem cell transplantation. Within 6(More)
POEMS syndrome is a rare plasma cell proliferative disorder characterized by polyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes. The patho-genesis of POEMS syndrome is still not well understood, but the overproduction of vascular endothelial growth factor (VEGF) probably secreted by plasma cells is thought to be responsible. 1(More)
  • M Nezu, H Oh, +10 authors T Asai
  • 1996
A 46-year-old man with idiopathic thrombocytopenic purpura (ITP) refractory to corticosteroid, splenectomy and other drugs was admitted to our hospital in August, 1994, because of aseptic necrosis of the right femoral head. Although high-dose intravenous gamma-globulin was ineffective, the platelet count was increased within two weeks by the combination(More)
Between July, 1990 and March, 1994, 31 patients with hematological malignancies or severe aplastic anemia underwent allogeneic bone marrow transplantation (BMT) at the Second Department of Internal medicine, Chiba University Hospital. Among the 29 evaluable patients who survived over 100 days after transplant, 11 patients (37.9%) developed late-onset(More)