Richard K. Cho

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POEMS syndrome is a rare plasma cell proliferative disorder characterized by polyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes. The pathogenesis of POEMS syndrome is still not well understood, but the overproduction of vascular endothelial growth factor (VEGF) probably secreted by plasma cells is thought to be responsible. High-dose(More)
Polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes syndrome is a rare multisystem disorder. Overproduction of vascular endothelial growth factor (VEGF) by plasmocytoma could be responsible for the symptoms. The authors treated four patients with high-dose chemotherapy and autologous peripheral blood stem cell transplantation. Within 6(More)
As a source of hematopoietic stem cells for transplantation, the use of peripheral blood stem cells (PBSCs) has become routine and comparable to that of the use of bone marrow. Recently, elderly patients with hematological malignancies also have been allowed to receive minitransplantations with nonmyeloablative conditioning regimens under sufficient PBSC(More)
  • M Nezu, H Oh, +10 authors T Asai
  • [Rinshō ketsueki] The Japanese journal of…
  • 1996
A 46-year-old man with idiopathic thrombocytopenic purpura (ITP) refractory to corticosteroid, splenectomy and other drugs was admitted to our hospital in August, 1994, because of aseptic necrosis of the right femoral head. Although high-dose intravenous gamma-globulin was ineffective, the platelet count was increased within two weeks by the combination(More)