Richard Hosking

Learn More
Expression of the neuropeptide galanin is markedly upregulated within the adult dorsal root ganglion (DRG) after peripheral nerve injury. We demonstrated previously that the rate of peripheral nerve regeneration is reduced in galanin knock-out mice, with similar deficits observed in neurite outgrowth from cultured mutant DRG neurons. Here, we show that the(More)
Advances in cannabis research have paralleled developments in opioid pharmacology whereby a psychoactive plant extract has elucidated novel endogenous signalling systems with therapeutic significance. Cannabinoids (CBs) are chemical compounds derived from cannabis. The major psychotropic CB delta-9-tetrahydrocannabinol (Delta(9)-THC) was isolated in 1964(More)
The chimeric peptide M35 (galanin(1-3)-bradykinin(2-9)amide) is a high-affinity galanin receptor ligand which acts as a galanin receptor antagonist in many experimental models such as the flexor reflex and chronic constriction injury in rat. However, more recently there have been conflicting reports that M35 may act as a galanin receptor agonist in certain(More)
Understanding the impacts of copyright is a challenge for the sharing and reuse of our research data. There is growing recognition of the problem, but the legal knowledge required to navigate through the minefield of restrictions and risks is often too difficult to uncover and understand. As of yet there are no appropriate tools to aid researchers,(More)
In this paper we explore two questions that we feel are important to investigate further if geographic information observatories are to be fruitful research endeavor in GIScience. The first question is simply ‘what is a geographic information observatory (and what is it not)?’ and the second question is ‘what use is a geographic information observatory?’.(More)
  • 1