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Partitioning glucose distribution/transport, disposal, and endogenous production during IVGTT.
TLDR
It is concluded that, in healthy subjects during an IVGTT, the two peripheral insulin effects account jointly for approximately one-half of the overall insulin-stimulated glucose lowering, each effect contributing equally.
Factors affecting the progression of renal disease in autosomal-dominant polycystic kidney disease
TLDR
The identification of unalterable maleficent factors such as the PKD1 gene and male gender permit more informed counseling while the identification of alterable factors suchAs hypertension, number of pregnancies and recurrent urinary tract infections provides the clinician with the opportunity to modify these factors and improve the management of patients with autosomal-dominant polycystic kidney disease.
The effect of a six-month exercise program on very low-density lipoprotein apolipoprotein B secretion in type 2 diabetes.
TLDR
It is demonstrated that in type 2 diabetes, a supervised exercise program reduces VLDL apolipoprotein (apo)B pool size, which may be due to a decrease in V LDL apoB secretion rate.
The metabolites citrate, myo‐inositol, and spermine are potential age‐independent markers of prostate cancer in human expressed prostatic secretions
TLDR
Proton nuclear magnetic resonance spectroscopy (1H‐NMRS) is used to assess potential metabolic markers of prostate cancer (PCa) in human expressed prostatic secretions (EPS) in this study.
Poor maternal nutrition leads to alterations in oxidative stress, antioxidant defense capacity, and markers of fibrosis in rat islets: potential underlying mechanisms for development of the diabetic
TLDR
It is concluded that maternal protein restriction causes age‐associated increased oxidative stress, impairment of oxidative defense, and fibrosis, which provides mechanisms by which suboptimal early nutrition can lead to T2D development later in life.
Insulin-like growth factor I has a direct effect on glucose and protein metabolism, but no effect on lipid metabolism in type 1 diabetes.
TLDR
IGF-I had a direct effect on glucose and protein metabolism, which was maintained during the hyperinsulinemic euglycemic clamp, which suggests that IGF-I acts in concert with insulin and may have an important role in maintaining glucose homeostasis andprotein metabolism in type 1 diabetes.
Sex Differences in Age-Related Stiffening of the Aorta in Subjects With Type 2 Diabetes
TLDR
Type 2 diabetes is associated with a greater age-related stiffening of the aorta in women compared with men, and this is not explained by hypertension.
Factors affecting the progression of renal disease in autosomal-dominant polycystic kidney disease.
TLDR
The identification of unalterable maleficent factors such as the PKD1 gene and male gender permit more informed counseling while the identification of alterable factorssuch as hypertension, number of pregnancies and recurrent urinary tract infections provides the clinician with the opportunity to modify these factors and improve the management of patients with autosomal-dominant polycystic kidney disease.
Insulin Detemir Reduces Weight Gain as a Result of Reduced Food Intake in Patients With Type 1 Diabetes
TLDR
The reduced weight gain with insulindetemir compared with NPH insulin is attributed to reduced energy intake rather than increased energy expenditure, and may be mediated by a direct or indirect effect of insulin detemir on the hormones that control satiety.
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