Richard G. Marsanico

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Rats were trained to intravenously self-administer d-amphetamine (.01 mg/kg/reward infusion) during daily 1-hr. testing sessions. Following removal of frontal cortex, rates of d-amphetamine self-administration were higher at early (3-5 days) postoperative intervals but lower at later (2-4 wk.) postoperative intervals. These and other results indicated that,(More)
Rats trained to bar-press on a FI 15 sec schedule for water reinforcement were administered various doses of d-amphetamine (0.25–4.0 mg/kg) both before and 6–8 weeks after bilateral ablation of frontal cortex. Preoperatively, low doses (e.g. 0.25–0.5 mg/kg) of (d-amphetamine increased responding and high doses (e.g. 2.0–4.0 mg/kg) of d-amphetamine depressed(More)
1 Apomorphine and pilocarpine each produced dose-dependent hypothermic effects in mice. However, the dose-response curve for pilocarpine was steeper than that for apomorphine.2 Bilateral lesions of the caudate nucleus produced a permanent decrease in sensitivity to apomorphine but had no effect on sensitivity to pilocarpine.3 Apomorphine and pilocarpine had(More)
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