Richard F. Addison

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A suite of 37 polybrominated diphenyl ether (PBDE) congeners and all of the homologue groups from mono- to deca-brominated were determined in ringed seal (Phoca hispida) blubber collected from subsistence hunts in the Canadian Arctic in 1981, 1991, 1996, and 2000. Total PBDE (sum(PBDE)) concentrations have increased exponentially over this period in male(More)
To assess chemical contaminant stress in the marine environment, ethoxyresorufin-O-deethylase (EROD) activity and cytochrome P450 1A (CYP1A) expression were measured in 88 English Sole (Pleuronectes vetulus) collected during May and June 1999 from four sites in Vancouver Harbour and at an expected reference site outside the harbour. Hepatic microsomes were(More)
The harbor seal (Phoca vitulina) can serve as a useful indicator of food web contamination by persistent organic pollutants (POPs) because of its high trophic level, wide distribution in temperate coastal waters of the Northern Hemisphere, and relative ease of capture. In 1996 through 1997, we live-captured 60 harbor seal pups from three regions, spanning(More)
After the Hebei Spirit oil spill incident (7th December, 2007) in the west coast of Korea, contamination of biliary PAH metabolite and hepatic biomarkers in a pelagic and a benthic fish was monitored for 1 year. Concentrations of 16 PAHs and alkylated PAHs in fish muscle were highest (22.0 ng/g d.w. for 16 PAHs and 284 ng/g d.w. for alkylated PAHs) at 5(More)
Polybrominated diphenyl ether (PBDE) concentrations were measured in the blubber of five mother-pup pairs of grey seals (Halichoerus grypus) from Sable Island, Nova Scotia (NS) sampled in 1995 and in 20 harbour seals (Phoca vitulina) from British Columbia (BC) sampled in 1991-1992. Concentrations in maternal grey seals from Sable Island averaged 112+/-55.2(More)
In blubber from maternal grey seals (Halichoerus grypus) from Sable Is., NS, sigma DDT (p,p'-DDE and p,p'-DDT) concentrations declined from 12 micrograms/g lipid in 1974 to 0.5 microgram/g in 1994. Pup blubber sigma DDT concentrations were about 60% of those of their mothers, and declined at similar rates. In maternal seals, p,p'-DDE increased from 56%(More)
Blubber of harbour seals (Phoca vitulina) sampled from the Strait of Georgia, BC, in 1991 and 1992 contained higher concentrations of polychlorinated dibenzo-p-dioxins and furans (PCDD/F) than did samples from Quatsino Sound on western Vancouver Island. The higher proportions of 1,2,3,6,7,8-hexachlorodibenzodioxin and 2,3,7,8-tetrachlorodibenzofuran in the(More)
Cholinesterases (ChEs) have been characterized in marbled sole (Limanda yokohamae) for use as a possible biomarker of pollution exposure. In brain, ChEs existed almost exclusively (>95%) as acetylcholinesterase (AChE) whereas in muscle, about 20-30% of ChE activity was in the form of butyrylcholinesterase (BChE; pseudocholinesterase). Acetylthiocholine and(More)
zyme. The application of 10 units/L HRP was sufficient to remove 95% of the 2,4-DCP at the concentration of 600 pg/L. This result cannot be generalized to all aromatic compounds. There appear to be several products of HRP reactions, depending on the substrate. These include polyphenols with carbon-carbon bonds on an aromatic ring, chlorinated furans, and(More)
Polychlorinated biphenyls (PCBs) have entered the environment in North America as Aroclor technical mixtures. Most methods used for the determination of total PCB levels in environmental samples visually match patterns of sample peaks to those in Aroclor standards. Concern over the accuracy of Aroclor-based measurements on compositionally modified samples(More)