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- Geoffrey J. McLachlan, Richard Bean, David Peel
- Bioinformatics
- 2002

MOTIVATION
This paper introduces the software EMMIX-GENE that has been developed for the specific purpose of a model-based approach to the clustering of microarray expression data, in particular, of… (More)

- Geoffrey J. McLachlan, David Peel, Richard Bean
- Computational Statistics & Data Analysis
- 2003

We focus on mixtures of factor analyzers from the perspective of a method for model-based density estimation from high-dimensional data, and hence for the clustering of such data. This approach… (More)

- Geoffrey J. McLachlan, Richard Bean, Liat Ben-Tovim Jones
- Bioinformatics
- 2006

MOTIVATION
An important problem in microarray experiments is the detection of genes that are differentially expressed in a given number of classes. We provide a straightforward and easily implemented… (More)

- Geoffrey J. McLachlan, Richard Bean, Liat Ben-Tovim Jones
- Computational Statistics & Data Analysis
- 2007

Mixtures of factor analyzers enable model-based density estimation to be undertaken for high-dimensional data, where the number of observations n is small relative to their dimension p. However, this… (More)

- Francesco Stellato, Dominik Oberthuer, +17 authors Henry N. Chapman
- IUCrJ
- 2014

A new approach for collecting data from many hundreds of thousands of microcrystals using X-ray pulses from a free-electron laser has recently been developed. Referred to as serial crystallography,… (More)

Finite mixture models are being increasingly used to model the distributions of a wide variety of random phenomena and to cluster data sets. In this paper, we focus on the use of normal mixture… (More)

- Richard Bean, Ebadollah S. Mahmoodian
- Discrete Mathematics
- 2001

A critical set in an nxn array is a set C of given entries, such that there exists a unique extension of C to an nxn Latin square and no proper subset of C has this property. The cardinality of the… (More)

- Peter Adams, Richard Bean, Abdollah Khodkar
- Ars Comb.
- 2003

A critical set in a Latin square of order n is a set of entries from the square which can be embedded in precisely one Latin square of order n, Such that if any element of the critical set. is… (More)

A unified approach of mixed-effects model has been recently proposed for clustering correlated genes from different kinds of microarray experiments. With the so-called EM-based MIXture analysis WIth… (More)

An important and common problem in microarray experiments is the detection of genes that are differentially expressed in a given number of classes. As this problem concerns the selection of… (More)