Richard Anthony Wardle

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The treatment of pulmonary hypertension (PH) secondary to bronchopulmonary dysplasia (BPD) in infants has evolved in recent years, improving both quality of life and survival for patients. One of the potential agents for this condition is sildenafil, a phosphodiesterase-V inhibitor with proven efficacy within the idiopathic PH population. However, only(More)
In the UK, key professional organizations have joined to provide inflammatory bowel disease (IBD) standards to be delivered by the NHS, highlighting the importance of patient education and support. The Crohn's and Colitis Knowledge Score (CCKNOW) is a validated multiple-choice questionnaire on the subject of IBD that is able to objectively quantify the(More)
BACKGROUND In the UK Inflammatory Bowel Disease (IBD) Standards have highlighted the importance of patient education and support [1]. Little literature exists however regarding the impact of these standards on patient's understanding of their disease. AIM To utilise the Crohn's and Colitis Knowledge Score (CCKNOW) to assess patient knowledge and make a(More)
The relationship between socioeconomic status (SES) and inflammatory bowel disease (IBD) is controversial. To date, research has focused on effects on incidence and prevalence, disease management and clinical outcomes; however, conclusions remain uncertain. This review examines current evidence, identifies what remains to be understood and explores the(More)
BACKGROUND Pulmonary hypertension is a condition of complex aetiology that culminates in right heart failure and early death. Soluble guanylate cyclase (sGC) stimulators are a promising class of agents that have recently gained approval for use. OBJECTIVES To evaluate the efficacy of sGC stimulators in pulmonary hypertension. SEARCH METHODS We searched(More)
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