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SUMMARY The results of bioassays of fractions of cigarette smoke con densate (CSC) using mice previously treated with 7,12-dimeth ylbenz[a@ anthracene (DMBA) are reported. The assay was designed to detect complete carcinogens as well as fractions possessing only tumor-promoting activity. The results showed that the weak acid (phenol) fraction and two(More)
Most of the tumorigenicity of CSC for animals can be con centrated in the neutral and acidic fractions. In an early study (19), roughly quantitative results showed that, although the major tumor-initiating activity was concentrated in the carbon tetrachloride eluate from silicic acid chromatography of the neutrals, some activity was found in the hexane(More)
BACKGROUND Supraventricular arrhythmias (SVA) are common after thoracic surgery and are associated with increased morbidity and mortality. This prospective, randomized, double-blind, placebo-controlled trial examined the effects of perioperative magnesium on the development of postoperative SVA. METHODS Two hundred patients undergoing thoracotomy for(More)