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  • Carlo Baldassi, Marco Zamparo, +4 authors Andrea Pagnani
  • Biology, Medicine, Physics, Mathematics
  • PloS one
  • 2014 (First Publication: 24 March 2014)
  • In the course of evolution, proteins show a remarkable conservation of their three-dimensional structure and their biological function, leading to strong evolutionary constraints on the sequenceContinue Reading
  • Francesco Neri, Danny Incarnato, +5 authors Salvatore Oliviero
  • Biology, Medicine
  • Genome Biology
  • 2013 (First Publication: 29 August 2013)
  • BackgroundTen-Eleven Translocation (TETs)proteins mediate the oxidation of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC). Tet1 is expressed at high levels in mouse embryonic stem cellsContinue Reading
  • Rémi Monasson, Riccardo Zecchina, Scott Kirkpatrick, Bart Selman, Lidror Troyansky
  • Mathematics, Physics, Computer Science
  • Random Struct. Algorithms
  • 1999 (First Publication: 6 October 1999)
  • Heuristic methods for solution of problems in the NP-Complete class of decision problems often reach exact solutions, but fail badly at "phase boundaries", across which the decision to be reachedContinue Reading