Ricardo D. Gonzalez

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Temozolomide (TMZ) has recently been recommended as a novel approach in the management of aggressive pituitary tumors. Herein, we present the case of a 43-year-old man with a 20-year history of silent subtype 2 pituitary corticotroph adenoma. Nine surgical resections and radiotherapy had failed to provide a cure. Morphological evaluation of the tumor(More)
Total urogenital sinus mobilization has been applied to the surgical correction of virilized females and has mostly replaced older techniques. Concerns have been raised about the effect of this operation on urinary continence. Here we review the literature on this topic since the description of the technique 15 years ago. Technical aspects and correct(More)
Although the use of eponyms to describe specific surgical operations is often discouraged (1), the custom is so deeply ingrained in medical writing that readers inevitably encounter them. Therefore, for the sake of clarity in communications , one should strive to be correct in their use. A classic case of perpetuation of misin-formation is the use of(More)
a r t i c l e i n f o Deforestation is a leading cause of biodiversity loss and an important source of global carbon emissions. This means that there are important synergies between climate policy and conservation policy. The highest rates of deforestation occur in tropical countries, where much of the land at the forest frontier is managed informally by(More)
Since the first report in 2005, Roux-en-Y gastric bypass (RYGB) surgery has been linked to a variety of metabolic changes that alter kidney stone risk. The studies with the highest level of evidence, performed in non-stone forming patients before and after RYGB, cite a number of kidney stone risk factors, including a 25% increase in urinary oxalate, a 30%(More)
A commentary on Should the genitoplasty of girls with CAH be done in one or two stages? by González R and Ludwikowski BM. Front Pediatr (2014) 1:54. doi:10.3389/ fped.2013. 00054 In a recent opinion article (1), we incorrectly stated that to date no cases of gender dysphoria had been reported in 46,XX individuals with adrenogenital syndrome raised as(More)
Great controversies and misunderstandings have developed around the relatively recently coined term disorders of sex development (DSD). In this article, we question the wisdom of including XX individuals with congenital adrenal hyperplasia (CAH) in the DSD category and develop arguments against it based on the published literature on the subject. It is(More)
We present a case of an 87-year-old female who was evaluated for an 8.5 cm left sided renal mass concerning for malignancy. The patient was transiently thrombocytopenic over the previous 4 months with platelet counts ranging from 50,000 to 125,000 plt/mcL and experienced diffuse hemorrhage during radical nephrectomy with failure to achieve mechanical(More)
We reviewed retrospectively the results of transperitoneal minilaparoscopic pyeloplasty in children younger than 2 years. The surgical technique utilized as well as the retrograde placement of the stent is described in detail. Twenty-four consecutive children with a mean age of 7.9 months (range 1-23), a mean weight of 7.4 kg (range 4-12), and a mean(More)
BACKGROUND Copy number variation (CNV) is a potential contributing factor to many genetic diseases. Here we investigated the potential association of CNV with nonsyndromic cryptorchidism, the most common male congenital genitourinary defect, in a Caucasian population. METHODS Genome wide genotyping were performed in 559 cases and 1772 controls (Group 1)(More)