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STUDY DESIGN An open-label, multicentre study was conducted to evaluate the antihypertensive efficacy of a 4-week course of losartan 50 mg plus hydrochlorothiazide 12.5 mg in Asian patients with essential hypertension whose blood pressure had previously been treated with but not controlled by valsartan 80 mg. METHODS A total of 237 eligible patients with(More)
Secondary sicca syndrome has been described in silicotic and exposed nonpneumoconiotic individuals. Systemic autoimmune pathogenic mechanisms have been thought to be responsible. Salivary gland mineral deposition has not so far been implicated. We describe the case of a dental technician who sand-blasted dental prostheses and developed silicoproteinosis and(More)
Noncardiogenic pulmonary edema is a well recognized complication of upper airway obstruction. We report the case of a previously healthy 18-year-old male who presented this complication following laryngospasm after anesthesia. He developed severe pulmonary edema with hypoxemia, high cardiac output and low pulmonary capillary pressures. He was managed with(More)
We present two patients with diffuse interstitial lung disease attributed to two different forms of presentation of pneumonitis due to inhalation of isocyanates. The first case was acute and accidental and the second was due to longer workplace exposure. In both cases, clinical, radiological and lung function findings as well as results of bronchoalveolar(More)
The obstructive sleep apnea syndrome (OSAS) is associated to a increased risk of cardiovascular diseases, including stroke. However, it is not known the cause of this last association. In this work the authors carry out a brief review of the theories that explain the relationship between OSAS and stroke and comment the potential alterations in cerebral(More)
Orthotopic liver transplantation (THO) is the treatment of choice for a variety of liver diseases. The national experience before 1993 has been scarce. In November 1993 we started our experience in THO at Clínica Las Condes, as part of a multiorgan transplant program (liver, kidney, pancreas). Until January 1995 we have performed 14 THO in 13 recipients(More)
To analyze the prevalence of tuberculosis infection, tuberculin tests were given to 3,292 elementary school children in the first and second grades in the environs of Albacete (Spain) in 1992. There were 1,532 children aged 6 (122 vaccinated with BCG) and 1,760 children aged 7 (162 vaccinated); 51 children tested positive (20 who had been vaccinated and 31(More)