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We present HapFACS (ver. beta), a new open source software and API for generating FACS-based facial expressions on 3D virtual characters that have accompanying lip-synchronized animation abilities. HapFACS has two main usage scenarios: First, with the HapFACS software, users can generate repertoires of realistic FACS-validated facial expressions, either as(More)
We discuss our approach to developing a novel modality for the computer-delivery of Brief Motivational Interventions (BMIs) for behavior change in the form of a personalized On-Demand VIrtual Counselor (ODVIC), accessed over the internet. ODVIC is a multimodal Embodied Conversational Agent (ECA) that empathically delivers an evidence-based behavior change(More)
BACKGROUND It is well known that the development of brain oxidative stress is one of the most serious complications of arterial hypertension that evokes brain tissue damage. The aim of this study was to examine the effects of atorvastatin treatment (20 mg/kg/day), as an antioxidant, to prevent the brain tissue oxidative stress in the hypertensive (HTN)(More)
In this article, we present HapFACS 1.0, a new software/API for generating static and dynamic three-dimensional facial expressions based on the Facial Action Coding System (FACS). HapFACS provides total control over the FACS Action Units (AUs) activated at all levels of intensity. HapFACS allows generating faces with an individual AU or composition of AUs(More)
To determine the impact of mechanical heterogeneity on the distribution of regional flows and pressures in the injured lung, we developed an anatomic model of the canine lung comprised of an asymmetric branching airway network, which can be stored as binary tree data structure. The entire tree can be traversed using a recursive flow divider algorithm,(More)
To determine the impact of ventilation frequency, lung volume, and parenchymal stiffness on ventilation distribution, we developed an anatomically-based computational model of the canine lung. Each lobe of the model consists of an asymmetric branching airway network subtended by terminal, viscoelastic acinar units. The model allows for empiric dependencies(More)
P-selectin glycoprotein ligand-1 (PSGL-1) is constitutively expressed on leukocytes and was thought to be down-regulated with cell activation. However, this work shows the surprising finding of functional PSGL-1 up-regulation during acute inflammation. PSGL-1 function was studied in our autoperfusion assay, in which blood from a mouse carotid flows through(More)
We discuss the design and implementation of the prototype of an avatar-based health system aimed at providing people access to an effective behavior change intervention which can help them to find and cultivate motivation to change unhealthy lifestyles. An empathic Embodied Conversational Agent (ECA) delivers the intervention. The health dialog is directed(More)
Earlier works on personalized Web search focused on the click-through graphs, while recent works leverage social annotations, which are often unavailable. On the other hand, many users are members of the social networks and subscribe to social groups. Intuitively, users in the same group may have similar relevance judgments for queries related to these(More)
In this paper, we discuss a novel approach for the computer-delivery of Brief Motivational Interventions (BMIs) for health behavior change. We describe the basic elements of our system architecture, and focus on enabling a multimodal Embodied Conversational Agent (ECA) to deliver the health behavior change interventions empathetically by adapting, in(More)